ECB Slashes Rates Again: Will Jerome Powell Take This As Cue For Another Fed Rate Cut? Here's What Analysts Say
In a move to stimulate a sluggish economy, the European Central Bank (ECB) has cut interest rates for the third time this year. This decision comes almost a month after the Federal Reserve announced a bold 50 basis point rate cut.
What Happened: The ECB’s latest rate cut marks the first time in 13 years that the bank has made consecutive rate reductions.
The central bank is shifting its focus from battling inflation to encouraging economic growth, which has been trailing behind the United States for the past two years.
In June, Morgan Stanley had predicted that both the ECB and the U.S. Federal Reserve would cut rates in September, citing decelerating inflation in both regions.
Shortly, the ECB reduced interest rates by 25 basis points, signaling a shift in policy to moderate monetary restrictions. This move was anticipated as the ECB assessed the inflation outlook and the effectiveness of monetary policy transmission.
The Fed also followed suit with a 50 basis point rate cut in September, as announced by Jerome Powell, with the probability of further rate cuts in the future drawing differing opinions.
The Analyst: The ECB has not provided specific guidance on future rate changes, emphasizing that decisions will be data-driven and made “meeting by meeting.”
However, as described by economist Mohamed El-Erian in a recent Bloomberg interview, the Federal Reserve is moving away from data dependency and taking a more strategic approach to interest rate cuts.
When asked about the difference in how ECB and Federal Reserve address the rate cuts, El-Erian noted it is partly because different countries within the Eurozone experience inflation differently.
“But I do agree with the notion…the market right now is pricing the same amount of cuts from the ECB and the Fed. And I don’t think that’s going to happen. I think the ECB will cut more than the Fed,” he added.
See Also: Trump Faces Backlash After Suggesting Car AsseMbly In America Is So Simple A ‘Child Could Do’
Potential Difficulties: Meanwhile, Joachim Klement, an investment strategist at Panmure Liberum, expressed in an op-ed published in Reuters about concerns over the potential difficulties that the European Central Bank (ECB) and the U.S. Federal Reserve may encounter in managing the escalating national debt amid rate cuts.
The International Monetary Fund (IMF) recently introduced the concept of “fiscal r-star,” the real interest rate needed to maintain stable national debt levels when an economy is growing at potential and inflation is on target.
Based on current consensus projections for eurozone budget deficits and GDP growth, the ECB’s policy rate would need to drop to about 2.0% in the next three to five years to stabilize debt levels. The situation is more alarming in the U.S., where the fed funds rate would need to fall below 2.5% to prevent the country’s debt-to-GDP ratio from increasing.
Why It Matters: The ECB’s decision to cut rates again comes as part of a broader trend among global central banks.
Economists have earlier suggested that the ECB’s actions could trigger a wave of coordinated rate cuts by central banks worldwide, potentially increasing market volatility in the coming months.
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Automotive Aluminum Market to Reach $60.6 Billion, Globally, by 2033 at 8.7% CAGR: Allied Market Research
Wilmington, Delaware , Oct. 17, 2024 (GLOBE NEWSWIRE) — Allied Market Research published a report, titled, “Automotive Aluminum Market by Form (Sheet, Plate, Bar, Tube and Others), Vehicle Type (Light Commercial Vehicles, Heavy Commercial Vehicles, Passenger Cars and Others), and Application (Hood, Pillars, Hinges, Motors, Sunroof Railings and Others): Global Opportunity Analysis and Industry Forecast, 2024-2033″. According to the report, the automotive aluminum market was valued at $26.2 billion in 2023, and is estimated to reach $60.6 billion by 2033, growing at a CAGR of 8.7% from 2024 to 2033.
Prime determinants of growth
Advancements in aluminum alloys are pivotal in fueling the demand for automotive aluminum. These advancements encompass innovations in alloy compositions, manufacturing methods and treatments all geared towards augmenting the properties and functionality of aluminum utilized in automotive applications. By continually refining aluminum alloys manufacturers produce materials with true attributes to address diverse automotive needs. For instance, certain alloys are crafted to exhibit exceptional formability facilitating the creation of complicated shapes and designs in vehicle parts. In addition, other alloys are tailored to bolster corrosion resistance, thereby ensuring prolonged durability and resilience across different environmental settings. Such tailored properties make aluminum alloys indispensable in meeting the exacting standards of the automotive industry, driving the demand for automotive aluminum market growth.
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Report coverage & details:
Report Coverage | Details |
Forecast Period | 2024–2033 |
Base Year | 2023 |
Market Size in 2023 | $26.2 billion |
Market Size in 2033 | $60.6 billion |
CAGR | 8.7% |
No. of Pages in Report | 340 |
Segments Covered | Form, Vehicle Type, Application, and Region. |
Drivers | Advancements in aluminum alloy technology Regulatory support for lightweight materials. |
Opportunity | Advanced manufacturing techniques. |
Restraint | Recycling infrastructure constraints. |
The sheet segment maintains its dominance by 2033.
By form, the sheet segment held the highest market share in 2023 and is estimated to maintain its leadership status throughout the forecast period. Sheet is extensively utilized in automotive body panels, closures such as hoods and doors, and structural components due to its lightweight nature, formability, and corrosion resistance. The use of aluminum sheet allows for significant weight reduction in vehicles, contributing to improved fuel efficiency and performance.
The light commercial vehicles segment is expected to possess the highest market share till 2033.
By vehicle type, light commercial vehicles segment held the highest market share in 2023 and is estimated to dominate during the forecast period. Aluminum is commonly utilized in the construction of light commercial vehicles, such as vans, pickups, and smaller trucks. Light commercial vehicles often prioritize factors such as fuel efficiency, payload capacity, and maneuverability, all of which benefit from the lightweight properties of aluminum. Aluminum is frequently employed in body panels, chassis components, and structural reinforcements in light commercial vehicles, contributing to weight reduction and improved performance.
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The hoods segment is expected to possess the highest market share till 2033.
Based on the application, hoods segment held the highest market share in 2023 and is estimated to dominate during the forecast period. Hoods are increasingly common in modern vehicles thanks to their lightweight properties, which play a crucial role in enhancing fuel efficiency and handling. Automakers are opting for aluminum hoods to achieve significant weight reduction compared to traditional steel hoods, making aluminum the preferred material for boosting overall vehicle performance. Moreover, the use of aluminum hoods supports the structural integrity and safety of the vehicle. Despite being lighter, aluminum hoods maintain the necessary strength and durability to protect the engine compartment and absorb impact in the event of a collision. This combination of lightweight efficiency and robust performance makes aluminum hoods an ideal component for modern automotive design.
Asia-Pacific is expected to experience fastest growth throughout the forecast period.
Based on region, Asia-Pacific has emerged as the fastest-growing market for automotive aluminum in terms of revenue. The lightweight and recyclable properties of aluminum present promising solutions for improving fuel efficiency and reducing emissions within the automotive sector. As countries in Asia-Pacific experience rapid urbanization and a surge in vehicle demand, the necessity for sustainable and efficient automotive materials becomes increasingly critical. Automotive aluminum, with its capacity to lower vehicle weight and enhance performance while reducing environmental impact, perfectly aligns with the region’s sustainability goals. In addition, the abundant availability of raw materials and advanced manufacturing capabilities across many Asia-Pacific nations is fostering the widespread adoption of automotive aluminum, further driving market growth in the region.
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Leading Market Players: –
- Nippon Light Metal Holdings Co., Ltd
- Vedanta Aluminium & Power
The report provides a detailed analysis of these key players in the global automotive aluminum market. These players have adopted different strategies such as new product launches, collaborations, expansion, joint ventures, agreements, and others to increase their market share and maintain dominant shares in different regions. The report is valuable in highlighting business performance, operating segments, product portfolio, and strategic moves of market players to showcase the competitive scenario.
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Allied Market Research (AMR) is a full-service market research and business-consulting wing of Allied Analytics LLP based in Portland, Oregon. Allied Market Research provides global enterprises as well as medium and small businesses with unmatched quality of “Market Research Reports” and “Business Intelligence Solutions.” AMR has a targeted view to provide business insights and consulting to assist its clients to make strategic business decisions and achieve sustainable growth in their respective market domain.
Pawan Kumar, the CEO of Allied Market Research, is leading the organization toward providing high-quality data and insights. We are in professional corporate relations with various companies and this helps us in digging out market data that helps us generate accurate research data tables and confirms utmost accuracy in our market forecasting. Each and every data presented in the reports published by us is extracted through primary interviews with top officials from leading companies of domain concerned. Our secondary data procurement methodology includes deep online and offline research and discussion with knowledgeable professionals and analysts in the industry.
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Closed System Transfer Devices (CSTD) Market Size Set to Expand with a 10.0% CAGR, Reaching USD 3.6 Billion by 2034| Analysis by Transparency Market Research Inc.
Wilmington, Delaware, United States, Transparency Market Research, Inc. , Oct. 17, 2024 (GLOBE NEWSWIRE) — The value of the global closed system transfer devices (CSTD) market sector was estimated at US$ 1.2 billion in 2023. Between 2024 and 2034, it is expected to increase at a CAGR of 10.0%, reaching US$ 3.6 billion.
Public awareness campaigns promoting the risks associated with hazardous medications and the need to handle them with care have resulted in the growing usage of CSTDs. An educational program designed to make healthcare workers aware of the benefits of closed medication preparation and delivery systems should be aimed at healthcare workers.
By preventing contamination during transfer and administration, CSTDs contribute to maintaining pharmaceutical purity and effectiveness. Contamination can lead to serious financial losses or negatively impact patient results regarding expensive or delicate medications.
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In the medical field, patient safety is of utmost importance. CSTDs help to improve patient safety outcomes during chemotherapy and other drug delivery procedures by reducing the danger of drug exposure and contamination.
The general increase in healthcare spending, especially in industrialized nations, encourages the purchase of technology that enhances patient safety and care. Healthcare facilities must include CSTDs as an essential part of their infrastructure when they budget for safety precautions and regulatory compliance. With biosimilar medications becoming more widely available and being used, CSTDs are necessary for handling these medications.
Competitive Landscape
- ICU Medical
- Baxter
- B. Braun
- BD
- Equashield
- Yukon Medical
- Caragen Ltd.
- JMS Co. Ltd.
Key Findings of the Market Report
- Based on the product, the system segment is expected to drive the closed system transfer devices (CSTD) market.
- In terms of application, the nursing segment will be a major market for the closed system transfer devices (CSTD) market.
- Increasing distributor demand is expected to drive a closed system transfer devices (CSTD) market.
- A dominant position was held by North America in 2023 in the global closed system transfer devices (CSTD) market.
Global Closed System Transfer Devices (CSTD) Market: Growth Drivers
- The adoption of CSTDs is fueled by tightening requirements imposed by regulatory organizations, including the European Medicines Agency (EMA), US Pharmacopeia (USP), and the Occupational Safety and Health Administration (OSHA) regulating the handling of dangerous medications. To comply with these rules, patients and healthcare professionals must be protected from exposure to closed systems.
- Increasing global cancer incidence is causing doctors to use chemotherapy medications more frequently, which are often dangerous and must be handled carefully. A safer method of administering these medications is through CSTDs, which pose less risk of contamination and exposure for healthcare workers.
- A growing focus on protecting healthcare personnel from occupational dangers is driving healthcare institutions to invest in technology that improves workplace safety.
- A CSTD is considered to be an essential component of ensuring the safety of workers who are responsible for preparing and administering dangerous medications.
- Standards and safety measures are in greater demand as the global healthcare infrastructure grows, particularly in emerging nations. Using technologies such as CSTDs is one way of ensuring compliance with global safety standards.
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Global Closed System Transfer Devices (CSTD) Market: Regional Landscape
- North America is expected to drive the demand for CSTD in the coming years. North America, especially the United States and Canada, has some of the most stringent restrictions for handling dangerous medications. According to the US Pharmacopeia (USP) and the US Occupational Safety and Health Administration (OSHA), strict regulations protect healthcare professionals from hazardous material exposure.
- Due to the increasing rate of cancer in North America, there is a need for safe handling procedures as well as chemotherapy medications. In particular, the United States suffers from a considerable cancer burden that is primarily treated by chemotherapy. Therefore, CSTDs, which ensure safe medication administration, have a thriving market.
- Healthcare personnel in North America are strongly encouraged to prevent occupational hazards. Hospitals and other healthcare facilities prioritize worker safety over anything else, so they invest in tools like CSTDs to minimize the risk of exposure to dangerous medications.
- Modern clinics, hospitals, and specialty treatment facilities are all part of North America’s sophisticated healthcare network. As part of their regular practices, these hospitals are more likely to incorporate cutting-edge technologies, such as CSTDs, to enhance patient care and safety.
Global Closed System Transfer Devices (CSTD) Market: Key Players
Closed system transfer devices (CSTD) manufacturers invest heavily in research and development to improve their products. To increase their product portfolio and meet the demand from expanding healthcare facilities, closed system transfer devices (CSTD) companies have to leverage strategic collaborations, mergers, and acquisitions.
Key Developments
- In October 2023, EQUASHIELD, the industry leader in Closed System Transfer Devices (CSTDs) for hazardous drugs, announced that its EQUASHIELD® Syringe Unit has been cleared for full volume use by the FDA.
- Syringe units with closed plungers are designed to prevent deliberate and unintentional syringe plunger detachment and to allow the use of hazardous drugs up to the maximum nominal volume of the system.
Global Closed System Transfer Devices (CSTD) Market: Segmentation
By Product
- Needle-free Systems
- Needle Systems
- Vial Adaptors
- Syringe Adaptors
- Tubing Sets and Accessories
By Application
- Pharmacy
- Nursing
- Veterinary
By Distribution Channel
By Region
- North America
- Latin America
- Asia Pacific
- Europe
- Middle East & Africa
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Explore wide-ranging Coverage of TMR’s Healthcare Market Insights Landscape
- Influenza Diagnostics Market – The global influenza diagnostics market is estimated to flourish at a CAGR of 5.6% from 2023 to 2031. Transparency Market Research projects that the overall sales revenue for influenza diagnostics is estimated to reach US$ 2.0 billion by the end of 2031.
- Sharps Containers Market – The sharp containers accounted for US$ 701.1 million in 2022. A CAGR of 4.7% is projected from 2023 to 2031. The market is expected to reach US$ 1.0 billion by 2031. Developing economies generate more medical waste, particularly as their healthcare infrastructure expands. Healthcare facilities are increasingly relying on sharp containers as a safe and effective way to dispose of waste.
About Transparency Market Research
Transparency Market Research, a global market research company registered at Wilmington, Delaware, United States, provides custom research and consulting services. Our exclusive blend of quantitative forecasting and trends analysis provides forward-looking insights for thousands of decision makers. Our experienced team of Analysts, Researchers, and Consultants use proprietary data sources and various tools & techniques to gather and analyses information.
Our data repository is continuously updated and revised by a team of research experts, so that it always reflects the latest trends and information. With a broad research and analysis capability, Transparency Market Research employs rigorous primary and secondary research techniques in developing distinctive data sets and research material for business reports.
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Wound Care Market to Witness 3.1% CAGR by 2031 | SkyQuest Technology
Westford, USA, Oct. 17, 2024 (GLOBE NEWSWIRE) — SkyQuest projects that Wound Care Market will attain the value of USD 16.32 Billion by 2031, with a CAGR of 3.1% during the forecast period (2024-2031). The growth of wound care market can be attributed to factors such as increasing aging population, increasing incidence of chronic wounds, advancements in wound care technology. Furthermore, there is growing awareness of its importance that wound management and availability of advanced wound care products drives market growth.
Wound Care Market Overview:
Report Coverage | Details |
Market Revenue in 2023 | USD 13.18 Billion |
Estimated Value by 2031 | USD 16.32 Billion |
Growth Rate | Poised to grow at a CAGR of 3.1% |
Forecast Period | 2024–2031 |
Forecast Units | Value (USD Billion) |
Report Coverage | Revenue Forecast, Competitive Landscape, Growth Factors, and Trends |
Segments Covered | Product, Application, End-use, Mode of Purchase, Distribution Channel and Region |
Geographies Covered | North America, Europe, Asia Pacific, Middle East & Africa, Latin America |
Report Highlights | Updated financial information / product portfolio of players |
Key Market Opportunities | Rising Demand for Home Healthcare Solutions |
Key Market Drivers | Growing Prevalence of Chronic Diseases |
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Wound Care Market Segmental Analysis
The Global Wound Care Market is segmented into Product, Application, End Use, and Region.
Based on Product, the market is segmented into Advanced Wound Dressing, Surgical Wound Dressing, and Traditional Wound Dressing.
Based on Application, the market is segmented into Chronic Wound and Acute Wound.
Based on End Use, the market is segmented into Hospitals, Specialty Clinics, Home Healthcare, Physician’s Office, Nursing Homes, and Others.
By Region, the market is segmented into North America, Europe, Asia-Pacific, Middle East and Africa, and Latin America.
Institutional Sales Segment to Dominate Due to High Volume of Patients in Hospitals and Clinics
The institutional sales segment is dominating in the market. Manufacturers of wound care products can also sell the products directly to healthcare providers, such as hospitals and clinics, or to patients through direct-to-consumer marketing. This approach can provide significant potential on how it is distributed to enable manufacturers to build relationships with their customers. Marketing companies consist of direct distributors and specialists. Hospitals, clinics, wound care centers, and other health care facilities, such as nursing homes, long-term care facilities, research centers, and maternity care centers, often have contracts and relationships that it lasts longer with the distributors and manufacturers.
Home Healthcare Segment to Drive Market Due to Introduction of Single-use NPWT Systems
The home healthcare segment is expected to grow at the fastest pace at a CAGR of 5.51% during the forecast period. During the pandemic outbreak, home healthcare wound care products were more in demand. Wound care in home care centers begins primarily with the introduction of single-use NPWT systems. These devices are small, portable and easy to use. In addition, the cost of such wound healing also encourages patients to opt for home care facilities during their hospital stay.
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Asia Pacific is Growing Due to Increasing Incidence of Chronic Diseases
The Asia Pacific region is estimated to witness the highest growth in the wound care market at a CAGR of 4.8% during the forecast period. The presence of developing countries such as China, India and Japan are expected to drive the market growth in this region. This can be attributed to the increasing lifestyle changes that are contributing to the increased incidence of chronic diseases in the region. Furthermore, technological advancement, increasing age population, increasing incidence of chronic diseases like diabetes & cancer are expected to boost the growth of the regional market. Thus, Asia Pacific is expected to witness the fastest growth during the forecast period due to the aforementioned factors.
Drivers
- Growing Prevalence of Chronic Diseases
- Technological Advancements
- Rise in the Aging Population
Restraints
- Limited Awareness in Developing Regions
- Regulatory Hurdles and Approvals
- High Cost of Advanced Wound Care Products
Prominent Players in Wound Care Market
- Smith & Nephew
- Mölnlycke Health Care AB
- ConvaTec Group PLC
- Ethicon (Johnson & Johnson)
- Baxter International
- URGO Medical
- Coloplast Corp.
- Medtronic
- 3M
- Derma Sciences Inc. (Integra LifeSciences)
- Medline Industries
- Advancis Medical
- B. Braun Melsungen AG
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Key Questions Answered in Wound Care Market Report
- How big is the Global Wound Care Market?
- What are the key drivers of Global Wound Care Market size?
- Which is the fastest growing region in the Global Wound Care Market?
This report provides the following insights:
Analysis of key drivers (growing prevalence of chronic diseases, technological advancements, rise in the aging population), restraints (regulatory hurdles and approvals, high cost of advanced wound care products), opportunities (rising demand for home healthcare solutions), influencing the growth of Wound Care Market.
- Market Dynamics: Comprehensive information about the various products offered by the dominant players in the Wound Care Market.
- Product Development/Innovation: An overview of emerging trends, R&D activities and product launches in the Wound Care Market.
- Market Growth: Detailed information on profitable growing industries.
- Market Trends: Complete information about new products, emerging geographical areas and recent developments in the market.
- Competitive Analysis: An in-depth analysis of the market segments, growth strategies, revenue analysis, and products of the key market players.
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Checkout More Related Studies Published by SkyQuest Technology:
Advanced Wound Care Market is growing at a CAGR of 5.4% in the forecast period (2024-2031)
Pressure Ulcers Treatment Market is growing at a CAGR of 5.2% in the forecast period (2024-2031)
Europe Home Healthcare Market is growing at a CAGR of 7.6% in the forecast period (2024-2031)
Low Trauma/Skin Friendly Adhesives Market is growing at a CAGR of 6.7% in the forecast period (2024-2031)
Europe Advanced Wound Care Market is growing at a CAGR of 6% in the forecast period (2024-2031)
About Us:
SkyQuest is an IP focused Research and Investment Bank and Accelerator of Technology and assets. We provide access to technologies, markets and finance across sectors viz. Life Sciences, CleanTech, AgriTech, NanoTech and Information & Communication Technology.
We work closely with innovators, inventors, innovation seekers, entrepreneurs, companies and investors alike in leveraging external sources of R&D. Moreover, we help them in optimizing the economic potential of their intellectual assets. Our experiences with innovation management and commercialization have expanded our reach across North America, Europe, ASEAN and Asia Pacific.
Contact Us:
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Skyquest Technology
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Westford,
Massachusetts 01886
USA (+1) 351-333-4748
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Supernus Announces Promising Data from Open-Label Phase 2a Study of SPN-820 in Adults with Major Depressive Disorder
Phase 2a study demonstrated rapid and substantial decrease in depressive symptoms
SPN-820 was well-tolerated with few adverse events
SPN-820 is a novel, first-in-class intracellular modulator of mTORC1 for the treatment of depression
Company to host webcast today at 4:30 p.m. ET to discuss the topline data
Topline results from Phase 2b randomized double-blind placebo-controlled study of SPN-820 in adults with treatment-resistant depression expected first-half 2025
ROCKVILLE, Md., Oct. 17, 2024 (GLOBE NEWSWIRE) — Supernus Pharmaceuticals, Inc. SUPN, a biopharmaceutical company focused on developing and commercializing products for the treatment of central nervous system (CNS) diseases, today announced data from its exploratory open-label Phase 2a clinical study of SPN-820 in adults with major depressive disorder. The study examined the safety and tolerability of SPN-820 2400 mg given once every 3 days as an adjunctive treatment to the current baseline antidepressant therapy, as well as assessed the rapid onset of improvement in depressive symptoms. The analysis is based on 40 enrolled subjects, of which 38 completed the 10-day treatment period.
Summary of the Data
- Clinically meaningful improvement of –6.1 at two hours and –9.6 at Day 10 on the Hamilton Depression Rating Scale-6 Items (HAM-D6) total score.
- Clinically meaningful improvement of –16.6 at four hours and –22.9 at Day 10 on the Montgomery Åsberg Depression Rating Scale (MADRS) total score.
- Suicidal ideation decreased by 80% (12.5% with suicidal ideation at baseline decreased to 2.6% with suicidal ideation at Day 10).
- SPN-820 was well-tolerated with few adverse events (AEs) and had acceptable tolerability with a discontinuation rate of 2.5% due to AEs.
- Most common AEs related to the drug included headache, nausea, somnolence, and dizziness. Additional AEs such as cognitive disorder, dry mouth, fatigue, nasal decongestion, and paresthesia oral were observed.
“These Phase 2a data underscore our belief that SPN-820 has the potential as a novel treatment option for patients with depression, with the opportunity to decrease symptoms quickly and without certain burdensome side effects,” said Jack Khattar, President and CEO of Supernus. “We expect to complete enrollment in the Phase 2b randomized double-blind placebo-controlled study of SPN-820 in adults with treatment-resistant depression in November of this year, with topline results expected in the first half of 2025.”
Webcast Details
Supernus will host a conference call and webcast today, October 17, 2024, at 4:30 p.m. ET to discuss these topline results. A live webcast with presentation slides will be available via this webcast link or in the Events & Presentations section of the Company’s Investor Relations website at www.supernus.com/Investors. Following management’s prepared remarks and discussion of the interim trial results, the call will open for questions.
Participants may also pre-register any time before the call here. Once registration is completed, participants will be provided a dial-in number with a personalized conference code to access the call. Please dial in 15 minutes prior to the start time.
Following the live call, a replay will be available on the Company’s Investor Relations website at www.supernus.com/Investors. The webcast will be available on the Company’s website for 60 days following the live call.
About SPN-820
SPN-820 is a first-in-class, orally active small molecule that increases the brain mechanistic target of rapamycin complex 1 (mTORC1) mediated synaptic function intracellularly. SPN-820 is being developed to provide a rapid-onset antidepressant response via oral administration for adult patients with depression. The compound has a novel mechanism of action that enhances synaptic activity and cellular metabolism in the brain and has demonstrated a rapid onset of action (signal at two hours) in early clinical studies. SPN-820 is expected to provide rapid antidepressant efficacy without potential dissociative side effects. A Phase 2b clinical study of SPN-820 in approximately 227 adult patients with treatment-resistant depression is ongoing.
About the SPN-820 Phase 2a Clinical Study
The study is a Phase 2a open-label study in 40 subjects with major depressive disorder (MDD). The primary objective of the study is to assess efficacy in MDD, as well as onset of efficacy and safety.
About Supernus Pharmaceuticals, Inc.
Supernus Pharmaceuticals is a biopharmaceutical company focused on developing and commercializing products for the treatment of central nervous system (CNS) diseases.
Our diverse neuroscience portfolio includes approved treatments for epilepsy, migraine, ADHD, hypomobility in Parkinson’s disease (PD), cervical dystonia, chronic sialorrhea, and dyskinesia in PD patients receiving levodopa-based therapy. We are developing a broad range of novel CNS product candidates including new potential treatments for hypomobility in PD, epilepsy, depression, and other CNS disorders.
For more information, please visit www.supernus.com.
Forward Looking Statements
This press release includes forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. These statements do not convey historical information but relate to predicted or potential future events that are based upon management’s current expectations. These statements are subject to risks and uncertainties that could cause actual results to differ materially from those expressed or implied by such statements. In addition to the factors mentioned in this press release, such risks and uncertainties include, but are not limited to, the Company’s reporting on preliminary and exploratory open label clinical study on SPN-820, the Company’s ability to sustain and increase its profitability; the Company’s ability to raise sufficient capital to fully implement its corporate strategy; the implementation of the Company’s corporate strategy; the Company’s future financial performance and projected expenditures; the Company’s ability to increase the number of prescriptions written for each of its products and the products of its subsidiaries; the Company’s ability to increase net revenue; the Company’s ability to commercialize its products and the products of its subsidiaries; the Company’s ability to enter into future collaborations with pharmaceutical companies and academic institutions or to obtain funding from government agencies; the Company’s ability to conduct and progress product research and development activities, including the timing and progress of the Company’s clinical trials, and projected expenditures; the Company’s ability to receive, and the timing of any receipt of, regulatory approvals to develop and commercialize the Company’s product candidates including SPN-820; the Company’s ability to protect its intellectual property and the intellectual property of its subsidiaries and operate its business without infringing upon the intellectual property rights of others; the Company’s expectations regarding federal, state and foreign regulatory requirements; the therapeutic benefits, effectiveness and safety of the Company’s product candidates including SPN-820; the accuracy of the Company’s estimates of the size and characteristics of the markets that may be addressed by its product candidates; the Company’s ability to increase its manufacturing capabilities for its products and product candidates including SPN-820; the Company’s projected markets and growth in markets; the Company’s product formulations and patient needs and potential funding sources; the Company’s staffing needs; and other risk factors set forth from time to time in the Company’s filings with the Securities and Exchange Commission made pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934, as amended. The Company undertakes no obligation to update the information in this press release to reflect events or circumstances after the date hereof or to reflect the occurrence of anticipated or unanticipated events.
CONTACTS:
Jack A. Khattar, President and CEO
Timothy C. Dec, Senior Vice President and CFO
Supernus Pharmaceuticals, Inc.
(301) 838-2591
or
INVESTOR CONTACT:
Peter Vozzo
ICR Westwicke
(443) 213-0505
peter.vozzo@westwicke.com
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Mortgage Rates Continue to Increase
MCLEAN, Va., Oct. 17, 2024 (GLOBE NEWSWIRE) — Freddie Mac FMCC today released the results of its Primary Mortgage Market Survey® (PMMS®), showing the 30-year fixed-rate mortgage (FRM) averaged 6.44 percent.
“The 30-year fixed-rate mortgage increased for the third consecutive week, moving closer to 6.5%,” said Sam Khater, Freddie Mac’s Chief Economist. “In general, higher rates reflect the strength in the economy that is supportive of the housing market. But notably, as compared to a year ago, rates are more than one percentage point lower and potential homebuyers can stand to benefit, especially by shopping around for the best quote as rates can vary widely between mortgage lenders.”
News Facts
- The 30-year FRM averaged 6.44 percent as of October 17, 2024, up from last week when it averaged 6.32 percent. A year ago at this time, the 30-year FRM averaged 7.63 percent.
- The 15-year FRM averaged 5.63 percent, up from last week when it averaged 5.41 percent. A year ago at this time, the 15-year FRM averaged 6.92 percent.
The PMMS® is focused on conventional, conforming, fully amortizing home purchase loans for borrowers who put 20 percent down and have excellent credit. For more information, view our Frequently Asked Questions.
Freddie Mac’s mission is to make home possible for families across the nation. We promote liquidity, stability, affordability and equity in the housing market throughout all economic cycles. Since 1970, we have helped tens of millions of families buy, rent or keep their home. Learn More: Website | Consumers | X | LinkedIn | Facebook | Instagram | YouTube
MEDIA CONTACT:
Angela Waugaman
(703)714-0644
Angela_Waugaman@FreddieMac.com
A photo accompanying this announcement is available at https://www.globenewswire.com/NewsRoom/AttachmentNg/1c0b88be-40a6-4f31-8bc9-41be51faecc3
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Medicare Trust Fund Under Fire: Critics Accuse VP Harris Of 'Highway Robbery' For Allegedly 'Violating' Vital Healthcare Resources
Vice President Kamala Harris is facing criticism over a new Medicare policy that’s stirring up controversy. Critics accuse her of backtracking on promises to safeguard the Medicare trust fund, sparking a fiery debate about whether the administration’s recent moves are helping or hurting the nation’s seniors.
Harris recently reassured the public that Medicare is a priority, telling AARP, “I will always fight to protect and strengthen Medicare for this and future generations.” She emphasized that big corporations and wealthy individuals must step up and pay their fair share, which she believes will help sustain critical programs like Medicare.
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But critics aren’t buying it. According to the latest Congressional Budget Office (CBO) analysis, a program introduced by the Centers for Medicare and Medicaid Services (CMS) to keep premiums low could cost taxpayers over $21 billion in the next three years.
This demonstration project, as it’s called, was designed to stabilize Medicare Part D premiums, which are set to rise sharply. Some, however, view it as a ploy to shield the administration from political fallout.
The plan stems from the Inflation Reduction Act, a bill to reduce drug costs for Medicare recipients. While the intent sounds good on paper, it comes with a significant catch: insurance companies will likely hike premiums substantially soon.
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With the average bids for Part D plans expected to triple by 2025, many argue that the administration’s subsidy plan is just a short-term patch on a long-term problem.
Stephen Moore, co-founder of the Heritage Foundation, didn’t mince words. “More highway robbery from the Dems on the Medicare trust fund,” he said, echoing concerns that the government is siphoning off money meant to protect seniors’ health care to fund other initiatives.
Sen. Chuck Grassley, a key Republican voice, was equally critical. He suggested that instead of facing the consequences of their policies, Democrats are using taxpayer dollars to mask the impact.
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“This nonpartisan CBO analysis confirms CMS’s cost-shifting plan is a dishonest election year gimmick to cover up those consequences,” Grassley said in a statement, calling the move an attempt to “artificially” lower premiums in time for the election.
The backlash on social media was swift. According to the advocacy group Commitment to Seniors, Harris has violated her pledge to secure Medicare.
They argue that this short-term fix could have long-term consequences for the trust fund, putting future generations at risk. “Seniors beware,” they wrote, warning of potential threats to the program the Vice President claimed she was protecting.
On the other side of the debate, administration defenders argue that the program provides necessary relief in an inflationary climate where drug prices and premiums are skyrocketing.
They emphasize that the Medicare trust fund still has safeguards in place and that the additional costs are a small price to pay for ensuring seniors don’t face crippling medical bills.
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This article Medicare Trust Fund Under Fire: Critics Accuse VP Harris Of ‘Highway Robbery’ For Allegedly ‘Violating’ Vital Healthcare Resources originally appeared on Benzinga.com
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Strong September Retail Sales Put Fed's Next Move In Doubt: Interest Rate Cuts Are 'Not A Slam Dunk'
A sharp rise in September retail sales is sparking fresh debate among economists about the Federal Reserve’s next move, as stronger-than-expected consumer resilience raises doubts about the need for further interest rate cuts.
Retail sales rose 0.4% month-over-month in the last month of the quarter, far exceeding the 0.1% growth recorded in August and surpassing economists’ forecasts of 0.3%. Even more notably, excluding volatile sectors like autos and gasoline, sales surged by 0.7%, marking the second-largest increase over the past 12 months.
The stronger-than-expected sales report is pushing analysts to rethink whether the Federal Reserve will move forward with another interest rate cut in November. While market participants overwhelmingly anticipate a 25 basis point reduction following the 50-basis-point move last month, the latest economic data may complicate that outlook.
Economists Debate On Fed Interest Rates
Quincy Krosby, chief global strategist at LPL Financial, said, “Retail sales came in well above expectations and continue to defy the weak economy thesis.”
Krosby added that the key question for monetary policy is whether the Fed will be concerned that the economy’s renewed strength could drive inflation higher.
However, she expects that a 25-basis-point cut will occur, especially if hurricane damage significantly impacts the labor market.
Speaking to CNBC, Stifel chief economist Lindsey Piegza said, “I think this was a very strong number and underscores the notion that the Fed maybe took too big of a step out of the gate with that 50 basis point cut.” Looking ahead, Piegza explained that there’s a stronger argument for a more patient approach, potentially holding off on a November cut.
Kathy Bostjancic, chief economist at Nationwide, also commented on the retail data: “That’s positive, right, for the overall economy. It’s really big consumer spending buoying the overall GDP growth in the US.”
Regarding the next Fed moves, Bostjancic added that “it’s not a slam dunk that they will cut rates.”
LPL Financial’s chief economist Jeffrey Roach maintains that the Fed will proceed with gradual cuts.
“Strong consumer spending in September suggests economic growth in the previous quarter was solidly above trend. Looking ahead, investors need to monitor any signs that the unemployed are finding it more difficult to earn a paycheck. Our baseline remains that the Fed will likely cut a quarter of a percent in both November and December.” Roach said.
Investors still largely anticipate a cut at the upcoming Fed meeting. Market-implied odds of a 25-basis-point rate cut in November dipped only slightly from 94% to 87% on Thursday.
Market Reactions: Treasury Yields Rise, Gold Hits Record Highs
Stronger-than-expected retail sales data, combined with a drop in unemployment claims, sparked a sharp rise in Treasury yields on Thursday, putting the brakes on further stock market gains.
The yield on the 10-year Treasury jumped 8 basis points to 4.10%, while the 30-year yield surged 9 basis points to 4.39%. This spike in yields hit Treasury-related assets hard, with the iShares 20+ Year Treasury Bond ETF TLT tumbling 1.5%. The surge in Treasury yields weighed on investor risk sentiment.
After opening 0.6% higher to fresh record highs, the S&P 500 was up just 0.3% by 12:15 p.m. in New York. The tech-heavy Nasdaq 100, tracked by the Invesco QQQ Trust QQQ, which had risen over 1% at the open, was up 0.7% at the time of publication.
Meanwhile, gold prices, as tracked by the SPDR Gold Trust GLD, rose 0.7%, hitting new all-time highs.
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